Jones Lab

• Siciliano CA, Karkhanis AN, Holleran KM, Melchior JR, Jones SR. Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure. Handb Exp Pharmacol. 2018 Apr 20. doi: 10.1007/164_2018_106. [Epub ahead of print] PMID: 29675581

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• Siciliano CA, Saha K, Calipari ES, Fordahl SC, Chen R, Khoshbouei H, Jones SR. Amphetamine Reverses Escalated Cocaine Intake via Restoration of Dopamine Transporter Conformation. J Neurosci. 2018 Jan 10;38(2):484-497. doi: 10.1523/JNEUROSCI.2604-17.2017. Epub 2017 Nov 24. PMID: 29175958

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• Shaw JK, Ferris MJ, Locke JL, Brodnik ZD, Jones SR, España RA. Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine. Addict Biol. 2017 Nov;22(6):1695-1705. doi: 10.1111/adb.12432. Epub 2016 Aug 2. PMID: 27480648

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• Melchior JR, Jones SR. Chronic ethanol exposure increases inhibition of optically targeted phasic dopamine release in the nucleus accumbens core and medial shell ex vivo. Mol Cell Neurosci. 2017 Sep 20. PMID: 28942046

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• Karkhanis A, Holleran KM, Jones SR. Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol, Drug, and Food Addiction. Int Rev Neurobiol. 2017;136:53-88. doi: 10.1016/bs.irn.2017.08.001. Epub 2017 Sep 12. PMID: 29056156

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• Siciliano CA, Jones SR. Cocaine Potency at the Dopamine Transporter Tracks Discrete Motivational States During Cocaine Self-Administration. Neuropsychopharmacology. 2017 Aug;42(9):1893-1904. PMID:28139678

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• Fordahl SC, Jones SR. High-Fat-Diet-Induced Deficits in Dopamine Terminal Function Are Reversed by Restoring Insulin Signaling. ACS Chem Neurosci. 2017 Jan 3. doi: 10.1021/acschemneuro.6b00308. [Epub ahead of print]

 

• Brust TF, Morgenweck J, Kim SA, Rose JH, Locke JL, Schmid CL, Zhou L, Stahl EL, Cameron MD, Scarry SM, Aubé J, Jones SR, Martin TJ, Bohn LM. Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria. Sci Signal. 2016 Nov 29;9(456):ra117.

• Karkhanis AN, Rose JH, Weiner JL, Jones SR. Early-Life Social Isolation Stress Increases Kappa Opioid Receptor Responsiveness and Downregulates the Dopamine System. Neuropsychopharmacology. 2016 Aug;41(9):2263-74. PubMed PMID: 26860203; PubMed Central PMCID: PMC4946054.

 

• Siciliano CA, Fordahl SC, Jones SR. Cocaine Self-Administration Produces Long-Lasting Alterations in Dopamine Transporter Responses to Cocaine. J Neurosci. 2016 Jul 27;36(30):7807-16. PubMed PMID: 27466327; PubMed Central PMCID: PMC4961771. 

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• Siciliano CA, Calipari ES, Cuzon Carlson VC, Helms CM, Lovinger DM, Grant KA, Jones SR. Voluntary ethanol intake predicts κ-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques. J Neurosci. 2015 Apr 15;35(15):5959-68. PubMed PMID: 25878269; PubMed Central PMCID: PMC4397597.  

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• Calipari ES, Siciliano CA, Zimmer BA, Jones SR. Brief intermittent cocaine self-administration and abstinence sensitizes cocaine effects on the dopamine transporter and increases drug seeking. Neuropsychopharmacology. 2015 Feb;40(3):728-35. PubMed PMID: 25212486; PubMed Central PMCID: PMC4289961.

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• Ferris MJ, España RA, Locke JL, Konstantopoulos JK, Rose JH, Chen R, Jones SR. Dopamine transporters govern diurnal variation in extracellular dopamine tone. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):E2751-9. doi: 10.1073/pnas.1407935111. PMID: 24979798

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• Calipari ES, Ferris MJ, Salahpour A, Caron MG, Jones SR. Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression. Nat Commun. 2013;4:2720. PubMed PMID: 24193139; PubMed Central PMCID: PMC4017736.